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235989

Sigma-Aldrich

Brij® L4

average Mn ~362

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Synonym(s):
Polyethylene glycol dodecyl ether, Polyoxyethylene (4) lauryl ether
Linear Formula:
(C20H42O5)n
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

description

non-ionic

Quality Level

mol wt

average Mn ~362

refractive index

n20/D 1.451 (lit.)

density

0.95 g/mL at 25 °C (lit.)

HLB

9

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCO

InChI

1S/C20H42O5/c1-2-3-4-5-6-7-8-9-10-11-13-22-15-17-24-19-20-25-18-16-23-14-12-21/h21H,2-20H2,1H3

InChI key

WPMWEFXCIYCJSA-UHFFFAOYSA-N

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1 of 4

This Item
STS021216005P1254
Brij® L4 average Mn ~362

235989

Brij® L4

ECO BRIJ® L4 average Mn ~362

STS0212

ECO BRIJ® L4

Brij® L23 main component: tricosaethylene glycol dodecyl ether

16005

Brij® L23

Brij® L23 suitable for Stein-Moore chromatography

P1254

Brij® L23

density

0.95 g/mL at 25 °C (lit.)

density

0.95 g/mL at 25 °C (lit.)

density

-

density

-

mol wt

average Mn ~362

mol wt

average Mn ~362

mol wt

-

mol wt

micellar avg mol wt 48,000, estimated mol wt 1198

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

200

HLB

9

HLB

9.7

HLB

-

HLB

16.9

refractive index

n20/D 1.451 (lit.)

refractive index

n20/D 1.451 (lit.)

refractive index

-

refractive index

-

General description

Brij® L4 is a non-ionic surfactant. It comprises an alkyl (C12) tail attached to an oxyethylene headgroup.

Application

Brij® L4 has been used:
  • as a surfactant for the synthesis of copper(I) oxide (Cu2O) spherical nanoparticles using a microemulsion technique
  • as a non-ionic surfactant for preparing reverse micelles to synthesize Pt3Co alloy nanoparticles
  • as a surfactant to enhance the efficiency of interfacial coupling of hydrophobic materials and to make hydrogel

Biochem/physiol Actions

Brij® L4 exhibits amphiphilic properties. Brij L4 contains hydrophobic and hydrophilic regions that can form micelles and disperse hydrophobic drugs into the core of micelles. This in turn enhances drug solubility. Brij L4 also elicits a strong inhibitory effect against breast cancer resistance protein (BCRP) mediated drug efflux. It inhibits Taq adsorption better when compared to other commonly used surfactants. Brij L4 supports droplet polymerase chain reaction (PCR) in picoliter reaction volumes at standard Taq concentrations.

Legal Information

Brij is a registered trademark of Croda International PLC

pictograms

Exclamation markEnvironment

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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