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MilliporeSigma

B4184

Brij® L23 solution

30 % (w/v) in H2O

Synonym(s):

Brij® 35 solution, C12E23, Polyoxyethylene (23) lauryl ether

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10 ML

$78.20

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$83.80

1 L

$265.00

1 GAL

$733.00

$78.20

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About This Item

CAS Number:
9002-92-0
MDL number:
MFCD00080891
UNSPSC Code:
12161900
PubChem Substance ID:
24891758
NACRES:
NA.25

Key Documents

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biological source

synthetic

Quality Level

200

description

non-ionic

form

liquid

mol wt

~1198.0 g/mol

concentration

30 % (w/v) in H2O

aggregation number

40

CMC

91 μM

transition temp

cloud point ≥100 °C

solubility

water: soluble

density

1.024 g/mL

HLB

16.9

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C58H118O24/c1-2-3-4-5-6-7-8-9-10-11-13-60-15-17-62-19-21-64-23-25-66-27-29-68-31-33-70-35-37-72-39-41-74-43-45-76-47-49-78-51-53-80-55-57-82-58-56-81-54-52-79-50-48-77-46-44-75-42-40-73-38-36-71-34-32-69-30-28-67-26-24-65-22-20-63-18-16-61-14-12-59/h59H,2-58H2,1H3

InChI key

IEQAICDLOKRSRL-UHFFFAOYSA-N

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1 of 4

This Item
16005235989STS0212
Brij® L23 solution 30 % (w/v) in H2O

Sigma-Aldrich

B4184

Brij® L23 solution

Brij® L23 main component: tricosaethylene glycol dodecyl ether

Sigma-Aldrich

16005

Brij® L23

Brij® L4 average Mn ~362

Sigma-Aldrich

235989

Brij® L4

ECO BRIJ® L4 average Mn ~362

Sigma-Aldrich

STS0212

ECO BRIJ® L4

form

liquid

form

pellets

form

-

form

semisolid (may be liquid)

aggregation number

40

aggregation number

-

aggregation number

-

aggregation number

-

CMC

91 μM

CMC

91 μM

CMC

-

CMC

-

HLB

16.9

HLB

-

HLB

9

HLB

9.7

density

1.024 g/mL

density

-

density

0.95 g/mL at 25 °C (lit.)

density

0.95 g/mL at 25 °C (lit.)

solubility

water: soluble

solubility

H2O: 40 mg/mL at 20 °C, clear to slightly hazy, colorless

solubility

-

solubility

water: insoluble

General description

Brij® L23, also known as Polyoxyethylene (23) lauryl ether, is an ethoxylated fatty alcohol derived from lauryl alcohol. It serves as a valuable non-ionic detergent widely utilized in biochemical studies. This versatile compound is particularly well-suited for protein solubilization and membrane protein isolation, making it a key component in various biochemical assays. Brij® L23′s non-ionic nature and unique properties also position it as an essential detergent for protein extraction and cell permeabilization, facilitating a broad spectrum of research in the same. Further, its use is instrumental in preserving the structural integrity and functionality of proteins, contributing significantly to studies involving proteins and their interactions in the area of biochemical research.

Application

Brij® L23 solution has been used:
  • as a supplement of De Man, Rogosa, Sharpe (MRS) broth for monitoring bacteriocin production by lactic acid bacteria(66)
  • as a component of developing buffer for the incubation of zymogram gel for metalloproteinase quantification(67)
  • as a component of activation buffer for recombinant human hepsin(68)

Biochem/physiol Actions

Brij® L23 solution is a surfactant and is used in the nanoparticle preparation by microemulsion method.[1]

Features and Benefits

High-purity product ideal for biochemical research applications

Packaging

Some bottles may appear indented due to the packaging process. This does not affect product integrity or quality.

Preparation Note

In the event that material is in the gel phase at room temperature, the customer should heat the material to a temperature range of greater than 35°C and less than 60°C, and stir the solution for approximately 15 minutes before use.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Legal Information

Brij is a registered trademark of Croda International PLC

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000483947
0000483945
0000483965
0000483965
0000483945

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Guillaume Morin et al.
Nutrients, 11(9) (2019-09-06)
Peroxides contaminating parenteral nutrition (PN) limit the use of methionine as a precursor of cysteine. Thus, PN causes a cysteine deficiency, characterized by low levels of glutathione, the main molecule used in peroxide detoxification, and limited growth in individuals receiving
Reverse microemulsion synthesis of CeO2 nanopowder using polyoxyethylene (23) lauryl ether as a surfactant
Pournajaf R, et al.
Ceramics International, 40(6), 8687-8692 (2014)
Darío Morais et al.
Rhinology, 50(1), 80-86 (2012-04-04)
Hereditary Haemorrhagic Telangiectasia or Rendu-Osler-Weber syndrome is a rare autosomal dominant vascular disease characterized by mucocutaneous and gastrointestinal telangiectases and localized arteriovenous malformations in lung, brain and liver. Epistaxis, due to rupture of telangiectases of the nasal mucosa, is the
N Shadid et al.
The British journal of surgery, 99(8), 1062-1070 (2012-05-26)
New minimally invasive treatment modalities, such as ultrasound-guided foam sclerotherapy (UGFS), are becoming more popular. In a multicentre randomized controlled non-inferiority trial, the effectiveness and costs of UGFS and surgery for treatment of the incompetent great saphenous vein (GSV) were
Amish Patel et al.
AJR. American journal of roentgenology, 199(4), 721-729 (2012-09-22)
The purpose of this review is to describe the clinical factors related to balloon-occluded retrograde transvenous obliteration, including the preparation needed, the technique and challenges, and the outcomes. Although the procedure can be performed when transjugular intrahepatic portosystemic shunt is
View All Related Papers

Articles

Enzymatic Assay of Cathepsin B

Cathepsin B is a lysosomal cysteine proteinase with broad specificity. This protocol uses Nα–CBZ–Arg–Arg–7–amido–4–methylcoumarin as the substrate for fluorometric detection of Cathepsin B activity.

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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