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556416

Sigma-Aldrich

New Methylene Blue N

Dye content ~70 %

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Synonym(s):
Basic Blue 24, Methylene Blue N
Empirical Formula (Hill Notation):
C18H22ClN3S
CAS Number:
Molecular Weight:
347.91
Colour Index Number:
52030
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.47

form

powder, crystals or chunks

composition

Dye content, ~70%

mp

190 °C (dec.) (lit.)

λmax

590 nm
632 nm (2nd)

εmax

≥29000 at 626-634 nm in water
≥30500 at 586-594 nm in water

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Cl-].CCNc1cc2[s+]c3cc(NCC)c(C)cc3nc2cc1C

InChI

1S/C18H22N3S.ClH/c1-5-19-13-9-17-15(7-11(13)3)21-16-8-12(4)14(20-6-2)10-18(16)22-17;/h7-10,19-20H,5-6H2,1-4H3;1H/q+1;/p-1

InChI key

NZYCYASKVWSANA-UHFFFAOYSA-M

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This Item
202096M5528M9140
vibrant-m

556416

New Methylene Blue N

vibrant-m

M5528

Methyl Blue

vibrant-m

M9140

Methylene blue

composition

Dye content, ~70%

composition

Dye content, 90%

composition

-

composition

Dye content, ≥82%

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

mp

190 °C (dec.) (lit.)

mp

>240 °C (dec.) (lit.)

mp

-

mp

-

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

form

powder, crystals or chunks

form

powder

form

powder

form

powder

Application

New methylene blue N has been used as a photosensitizer for the photodynamic inactivation of Candida albicans.

Biochem/physiol Actions

New methylene blue N can bind, neutralize and crosslink with RNA. This causes co-precipitation of ribosomal and residual RNA with the mitochondria and ferritin masses. These events make the living young erythrocytes as microscopically visible, dark-blue clusters and filaments, referred to as reticulum. New Methylene Blue N helps in counting of reticulocytes (erythrocytes containing RNA).

Features and Benefits

Solvent soluble cationic thiazine dye

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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