556416

New Methylene Blue N

Dye content ~70 %

• Synonym(s): Basic Blue 24, Methylene Blue N
• Empirical Formula (Hill Notation): C₁₈H₂₂ClN₃S
• CAS Number: 1934-16-3
• Molecular Weight: 347.91
• Colour Index Number: 52030
• EC Number: 217-696-9
• MDL number: MFCD00135878
• PubChem Substance ID: 24879556
• NACRES: NA.47

Properties

• form: powder, crystals or chunks
• composition: Dye content, ~70%
• mp: 190 °C (dec.) (lit.)
• λmax: 590 nm; 632 nm (2nd)
• εmax: ≥29000 at 626-634 nm in water; ≥30500 at 586-594 nm in water
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: [Cl-].CCNc1cc2[s+]c3cc(NCC)c(C)cc3nc2cc1C
• InChI: 1S/C18H22N3S.ClH/c1-5-19-13-9-17-15(7-11(13)3)21-16-8-12(4)14(20-6-2)10-18(16)22-17;/h7-10,19-20H,5-6H2,1-4H3;1H/q+1;/p-1
• InChI key: NZYCYASKVWSANA-UHFFFAOYSA-M

Description

Application

New methylene blue N has been used as a photosensitizer for the photodynamic inactivation of Candida albicans.

Packaging

1, 10 g in glass bottle

Biochem/physiol Actions

New methylene blue N can bind, neutralize and crosslink with RNA. This causes co-precipitation of ribosomal and residual RNA with the mitochondria and ferritin masses. These events make the living young erythrocytes as microscopically visible, dark-blue clusters and filaments, referred to as reticulum. New Methylene Blue N helps in counting of reticulocytes (erythrocytes containing RNA).

Features and Benefits

Solvent soluble cationic thiazine dye

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves