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C9538

Sigma-Aldrich

Coenzyme Q10

≥98% (HPLC)

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Synonym(s):
Q-10, Ubiquinone 50, Ubiquinone-10
Empirical Formula (Hill Notation):
C59H90O4
CAS Number:
Molecular Weight:
863.34
Beilstein/REAXYS Number:
1900141
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

color

yellow to dark orange

mp

49 °C

application(s)

cell analysis

storage temp.

−20°C

SMILES string

O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)\C)\C)\C)\C)\C)=C(C)C1=O

InChI

1S/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+

InChI key

ACTIUHUUMQJHFO-UPTCCGCDSA-N

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1 of 4

This Item
U0020000U002000107386
vibrant-m

C9538

Coenzyme Q10

vibrant-m

U0020000

Ubidecarenone

vibrant-m

07386

Coenzyme Q10

assay

≥98% (HPLC)

assay

-

assay

-

assay

≥97.5% (HPLC)

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

100

color

yellow to dark orange

color

-

color

-

color

faint yellow to dark orange

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

mp

49 °C

mp

49 °C

mp

49 °C

mp

49 °C

Application

Coenzyme Q10 (CoQ10) has been used:
  • as a bioactive compound to study its immune modulating properties in vitro
  • as a standard for high-performance liquid chromatography
  • to study its effect on exercised rat aorta
  • in the cellular CoQ uptake assay

Biochem/physiol Actions

Coenzyme Q10 is an endogenous cellular antioxidant and an essential component of the electron transfer chain. CoQ10 takes part in aerobic cellular respiration and generation of energy in the form of ATP.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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N Okudan et al.
Acta physiologica Hungarica, 99(1), 40-50 (2012-03-20)
In this study, the effect of long-term supplementation of coenzyme Q10 (CoQ10) on the responses of swim-trained rat aorta was investigated. Twenty-four adult male Wistar rats were divided into four groups: untrained, trained, untrained+CoQ10, and trained+CoQ10 group. In the trained
Steven Lunetta et al.
Journal of AOAC International, 91(4), 702-708 (2008-08-30)
An international collaborative study was conducted of a high-performance liquid chromatographic (HPLC)-UV method for the determination of coenzyme Q10 (CoQ10, ubidecarenone) in raw materials and dietary supplements. Ten collaborating laboratories determined the total CoQ10 content in 8 blind duplicate samples.
Lionel Van Maldergem et al.
Annals of neurology, 52(6), 750-754 (2002-11-26)
A 31-year-old woman had encephalopathy, growth retardation, infantilism, ataxia, deafness, lactic acidosis, and increased signals of caudate and putamen on brain magnetic resonance imaging. Muscle biochemistry showed succinate:cytochrome c oxidoreductase (complex II-III) deficiency. Both clinical and biochemical abnormalities improved remarkably
E L Appelkvist et al.
The Clinical investigator, 71(8 Suppl), S97-102 (1993-01-01)
Inhibitors of hydroxymethylglutaryl coenzyme A reductase are used clinically to decrease blood levels of low-density lipoprotein cholesterol in hypercholesterolemic patients. However, little is known about the possible effects of these inhibitors on dolichol and cholesterol synthesis. Oral administration of mevinolin
S Ogasahara et al.
Neurology, 35(3), 372-377 (1985-03-01)
In a patient with Kearns-Sayre syndrome, concentration of coenzyme Q10, a component of the mitochondrial electron transport system, was decreased in serum and in the mitochondrial fraction of skeletal muscle. Serum concentrations of lactate and pyruvate were abnormally high, especially

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