Skip to Content
MilliporeSigma

S7388

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide

Subtilisin substrate

Synonym(s):

N-Succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide, N-Succinyl-Ala-Ala-Pro-Phe-pNA

Slide 1 of 4
Sign In to View Organizational & Contract Pricing.

Select a Size

25 MG

$107.00

100 MG

$397.00

250 MG

$831.00

500 MG

$1,410.00

$107.00

Check Cart for Availability
Request a Bulk Order

About This Item

Empirical Formula (Hill Notation):
C30H36N6O9
CAS Number:
70967-97-4
Molecular Weight:
624.64
NACRES:
NA.32
PubChem Substance ID:
24899742
UNSPSC Code:
12352200
MDL number:
MFCD00077161
Beilstein/REAXYS Number:
4289896

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide,

InChI key

LKDMKWNDBAVNQZ-WJNSRDFLSA-N

SMILES string

[H][C@]1(CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CCC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)Nc3ccc(cc3)[N+]([O-])=O

InChI

1S/C30H36N6O9/c1-18(31-25(37)14-15-26(38)39)27(40)32-19(2)30(43)35-16-6-9-24(35)29(42)34-23(17-20-7-4-3-5-8-20)28(41)33-21-10-12-22(13-11-21)36(44)45/h3-5,7-8,10-13,18-19,23-24H,6,9,14-17H2,1-2H3,(H,31,37)(H,32,40)(H,33,41)(H,34,42)(H,38,39)/t18-,19-,23-,24-/m0/s1

storage temp.

−20°C

Quality Level

300

Gene Information

human ... FKBP10(60681)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
573462SML1424S4760
N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide

Sigma-Aldrich

S7388

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide

Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide Sensitive chromogenic substrate for human leukocyte cathepsin G that is not reactive with elastase.

Sigma-Aldrich

573462

Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide

Ac-YVAD-pNA ≥98% (HPLC)

Sigma-Aldrich

SML1424

Ac-YVAD-pNA

N-Succinyl-Ala-Ala-Ala-p-nitroanilide elastase substrate

Sigma-Aldrich

S4760

N-Succinyl-Ala-Ala-Ala-p-nitroanilide

Quality Level

300

Quality Level

100

Quality Level

100

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

Gene Information

human ... FKBP10(60681)

Gene Information

-

Gene Information

-

Gene Information

-

Biochem/physiol Actions

N-succinyl-Ala-Ala-Pro-Phe p-nitroanilide is a substrate for subtilisin[1] and proteases.[2]

General description

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide is a colorimetric substrate for chymotrypsin, human leukocyte cathepsin G and peptidyl prolyl isomerase.

Application

N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide has been used as a substrate to determine chymotrypsin activity.[3][4]
N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide has been used:
  • as a substrate for cathepsin G assay in bone marrow lysates.[5]
  • in proteolytic activity assay of serine protease subtilisin carlsberg (SC).[6]
  • as a substrate for neutrophil elastase, trypsin and chymotrypsin in protease assay.[7]

related product

Product No.
Description
Pricing

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000438426
0000438426
0000438438
0000438438
0000420705

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Interleukin-33 is activated by allergen-and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage
Scott IC, et al.
Scientific Reports, 8(1), 3363-3363 (2018)
Jolanda Neef et al.
Microbial cell factories, 16(1), 57-57 (2017-04-06)
The microbial cell factory Bacillus subtilis is a popular industrial platform for high-level production of secreted technical enzymes. Nonetheless, the effective secretion of particular heterologous enzymes remains challenging. Over the past decades various studies have tackled this problem, and major
J J Siekierka et al.
Nature, 341(6244), 755-757 (1989-10-26)
CYCLOSPORIN A and the newly discovered immunosuppressant, FK-506, are potent inhibitors of T cell activation. In addition to their clinical importance in the prevention of allograft rejection, cyclosporin A and FK-506 represent important reagents for the study of the molecular
Zinc oxide-montmorillonite hybrid influences diarrhea, intestinal mucosal integrity, and digestive enzyme activity in weaned pigs.
Hu C
Biological trace element research, 149(2), 190-196 (2012)
Improved Enantioselectivity of Subtilisin Carlsberg towards Secondary Alcohols by Protein Engineering
Dorau R, et al.
Chembiochem, 19(4), 338-346 (2018)
View All Related Papers

Articles

Chymotrypsin

Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.

Related Content

Product Information Sheet - S7388

Product Information Sheet

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service