Genome Engineering with CompoZr Custom Zinc Finger Nucleases (ZFNs)

Genome Editing is a powerful technique that can be used to elucidate gene function and the genetic basis of disease. CompoZr Zinc Finger Nucleases (ZFNs) may be used for genome editing and enable gene knockout, gene integration or gene modification for in vitro or in vivo applications by introducing a user-defined double stranded DNA break. Once the double stranded break is introduced taking advantage of either non-homologous end joining or homology directed repair enables the desired genetic outcome. This video describes the use of CompoZr ZFNs to create a gene knockout.

We offer the following products for gene editing:

  • Knockout ZFNs
  • Custom ZFN Service
  • Targeted Integration Kits

References

1.
Hansen K, Coussens MJ, Sago J, Subramanian S, Gjoka M, Briner D. (2012). Genome Editing with CompoZr Custom Zinc Finger Nucleases (ZFNs). J. Vis. Exp. (64), e3304.. DOI: 10.3791/3304

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.