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Merck

R4632

Retinil acetato

synthetic, crystalline solid or supercooled liquid

Sinonimo/i:

Retinolo acetato, Vitamina A acetato

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1 G

60,00 €

5 G

180,00 €

25 G

394,50 €

100 G

1.150,00 €

60,00 €


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Informazioni su questo articolo

Formula empirica (notazione di Hill):
C22H32O2
Numero CAS:
Peso molecolare:
328.49
NACRES:
NA.79
PubChem Substance ID:
eCl@ss:
34058009
UNSPSC Code:
12352205
EC Number:
204-844-2
MDL number:
Beilstein/REAXYS Number:
1915439

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Nome del prodotto

Retinil acetato, synthetic, crystalline solid or supercooled liquid

InChI key

QGNJRVVDBSJHIZ-QHLGVNSISA-N

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

biological source

synthetic

assay

≥90% (HPLC)

form

crystalline solid or supercooled liquid

potency

2,600,000-2,940,000 I.U. per g

color

light yellow to dark yellow

mp

57-58 °C
~58 °C (lit.)

storage temp.

−20°C

Quality Level

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Questo articolo
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Retinil acetato synthetic, crystalline solid or supercooled liquid

Sigma-Aldrich

R4632

Retinil acetato

Retinil acetato solid or viscous liquid, BioReagent, synthetic, suitable for cell culture

Sigma-Aldrich

R7882

Retinil acetato

Retinil acetato synthetic, matrix dispersion, 475,000-650,000 USP units/g

Sigma-Aldrich

R3250

Retinil acetato

Retinil acetato analytical standard

Supelco

46958

Retinil acetato

assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

-

assay

-

biological source

synthetic

biological source

synthetic

biological source

synthetic

biological source

-

form

crystalline solid or supercooled liquid

form

solid or viscous liquid

form

matrix dispersion

form

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-10 to -25°C

mp

57-58 °C, ~58 °C (lit.)

mp

57-58 °C

mp

57-58 °C

mp

57-58 °C

color

light yellow to dark yellow

color

light yellow to dark yellow

color

yellow

color

-

Analysis Note

Activity based on HPLC comparison to USP standard.

Application

Retinyl acetate has been used:
  • to study its effects on cochlear development in mice[1]
  • as a component of an internal standard to quantify antioxidants in yolk[1]
  • as an internal standard to determine serum retinol concentration[2]

Biochem/physiol Actions

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.
Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed. Retinyl acetate is used in a wide range of biological applications.

General description

Vitamin A usually occurs in food as retinyl esters,[3] which are the pre-formed sources of vitamin A.[4] Retinyl acetate exists as yellow crystals and is insoluble in water. It is soluble in ethanol and oils.[5]

Physical form

Packaged as a melt and may exist as a crystalline solid or a supercooled viscous liquid

pictograms

Health hazard

signalword

Danger

Hazard Classifications

Aquatic Chronic 4 - Repr. 1B

Classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Certificati d'analisi (COA)

Lot/Batch Number

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Assessment of the relative dose-response test based on serum retinol-binding protein instead of serum retinol in determining low hepatic vitamin A stores
Fujita M, et al.
American Journal of Clinical Nutrition (2009)

Protocolli

GB method with Ascentis® Express C30 column achieves baseline resolution for Vitamin A and E critical pair.

Domande

1–2 di 2 domande  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Utile?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Utile?

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