The absorption wavelength for detecting dexamethasone is approximately 240 nm. However, this product has not been measured for absorption.
D2915
Dexamethasone-Water Soluble
suitable for cell culture, BioReagent
別名:
デキサメサゾン-シクロデキストリン複合体
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この商品について
CAS番号:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
EC Number:
200-003-9
NACRES:
NA.77
Biological source:
synthetic (organic)
Form:
solid
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製品名
Dexamethasone-Water Soluble, suitable for cell culture, BioReagent
InChI
1S/C42H70O35.C22H30O4/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51;1-12-8-16-15-5-4-13-9-14(24)6-7-21(13,2)20(15)17(25)10-22(16,3)19(12)18(26)11-23/h8-63H,1-7H2;6-7,9,12,15-17,19-20,23,25H,4-5,8,10-11H2,1-3H3/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-;12-,15+,16?,17+,19-,20-,21+,22+/m11/s1
InChI key
XEJNDGTUKUMQNG-ARJMFYCQSA-N
SMILES string
C[C@@H]1CC2C3CCC4=CC(=O)C=C[C@]4(C)C3[C@@H](O)C[C@]2(C)[C@H]1C(=O)CO.OC[C@H]5O[C@@H]6O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]7CO)O[C@H]8[C@H](O)[C@@H](O)[C@H](O[C@@H]8CO)O[C@H]9[C@H](O)[C@@H](O)[C@H](O[C@@H]9CO)O[C@H]%10[C@H](O)[C@@H](O)[C@H](O[C@@H]%10CO)O[C@H]%11[C@H](O)[C@@H](O)[C@H](O[C@@H]%11CO)O[C@H]%12[C@H](O)[C@@H](O)[C@H](O[C@@H]%12CO)O[C@H]5[C@H](O)[C@H]6O
biological source
synthetic (organic)
product line
BioReagent
form
solid
technique(s)
cell culture | mammalian: suitable
solubility
H2O: 25 mg/mL, clear to slightly hazy
shipped in
ambient
storage temp.
room temp
Quality Level
1 of 4
当該品目 | D-085 | D4902 | D8893 |
|---|---|---|---|
| biological source synthetic (organic) | biological source - | biological source synthetic | biological source synthetic (organic) |
| Quality Level 200 | Quality Level 300 | Quality Level 200 | Quality Level 200 |
| product line BioReagent | product line - | product line BioReagent | product line BioXtra |
| form solid | form liquid | form powder | form powder |
| technique(s) cell culture | mammalian: suitable | technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable | technique(s) cell culture | mammalian: suitable, single cell analysis: suitable | technique(s) cell culture | mammalian: suitable |
| shipped in ambient | shipped in - | shipped in ambient | shipped in ambient |
Application
Biochem/physiol Actions
Other Notes
1グラムあたり約65 mgのデキサメタゾンが含有されています；-β-シクロデキストリンを天秤で量ります。
Packaging
容量はデキサメサゾンの量に基づいています。
Related product
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
保管分類
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Tissue-specific actions of glucocorticoids on apoptosis: a double-edged sword
Gruver-Yates A and Cidlowski J
Cells, 2(2), 202-223 (2013)
The effect of temperature on the viability of human mesenchymal stem cells
Reissis Y, et al.
Stem Cell Research & Therapy, 4(6), 139-139 (2013)
Mechanisms of dexamethasone-mediated inhibition of Toll-like receptor signaling induced by Neisseria meningitidis and Streptococcus pneumoniae
Mogensen TH, et al.
Infection and Immunity, 76(1), 189-197 (2008)
Glucocorticoid (dexamethasone)-induced metabolome changes in healthy males suggest prediction of response and side effects
Bordag N, et al.
Scientific Reports, 5, 15954-15954 (2015)
Dexamethasone inhibits interleukin-1beta-induced corneal neovascularization: role of nuclear factor-kappaB-activated stromal cells in inflammatory angiogenesis
Nakao S, et al.
The American Journal of Pathology, 171(3), 1058-1065 (2007)
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what is the wavelength of absorbance for detecting dexamethasone cyclodextrin complex in DI water in quantitative analysis?
1 回答-
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How long is Product D2915 stable in solid form?
1 回答-
For certain products, the certificate of analysis may only display the Release Date, without a specified Retest, Expiration, or Use-by-Date. In such cases, the standard warranty of 1 year from the date of shipment applies. This product should remain stable in solid form for at least 1 year if stored correctly. For additional information on the warranty, refer to the terms and conditions of sale. Product Dating Information.
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D2915 is light sensitive?
1 回答-
This material is considered light sensitive and is packaged in amber glass bottles.
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What is the molecular mass of Dexamethasone-Water Soluble (D2915)?
1 回答-
This product is a multi-component item comprised of dexamethasone and (2-Hydroxypropyl)-?-cyclodextrin. The molecular weight of Dexamethasone is 392.5 g/mol. The molecular weight of the (2-Hydroxypropyl)-?-cyclodextrin is variable, but has an average molecular weight of 1,396 g/mol. There is an excess of cyclodextrin in the mixture to greatly enhance the solubility of the dexamethasone. The product is sold on the basis of the Dexamethasone content. The final product will have 55 - 75 mg of Dexamethasone per gram solid. For example, a 100mg package reporting a 75mg/gram Dexamethasone concentration would be a package of 1.81 grams. This value is reported in the Certiicate of Analysis. Please see the link below to review a sample of a specific Certificate:
https://www.sigmaaldrich.com/US/en/product/sigma/d2915#product-information役に立ちましたか？
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How should stock solutions for item D2915-100MG be stored?
1 回答-
Stock solutions can be stored for up to 2 months at -20°C.
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What is the recommended method for storing prepared solutions of D2915 dexamethasone water-soluble?
1 回答-
The recommended method for storing prepared solutions of D2915 dexamethasone water-soluble is to store the solutions in working aliquots at -20°C.
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Is the 100mg labeled on the bottle of D2915 Dexamethasone for the total powder or the total dexamethasone?
1 回答-
Each vial contains 100 mg of dexamethasone. The mg of dexamethasone per gram is provided on the label, typically around 65 mg/g.
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Is additional solubility data available for product D2915, Dexamethasone-Water Soluble?
1 回答-
The solubility of product D2915, Dexamethasone-Water Soluble, has been tested only in water, with a solubility (turbidity) of clear to slightly hazy at 25 mg/mL in water. Additionally, It is also soluble in ethanol (25 mg/mL), DMSO (25 mg/mL), and DMF (25 mg/mL).
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Once this product has been reconstituted in water, how long can it be stored, and at what temperature?
1 回答-
Stock solutions may be stored in working aliquots at -20ºC. Please see the link below for additional information on the Water Soluble Complexes, including Dexamethasone, Water Soluble:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/218/859/e8014inf.pdf役に立ちましたか？
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Do you have references for the use of Product D2915, Dexamethason - Water Soluble?
1 回答-
Here is one reference that describes using Product No. D2915: Chang, C.-J., et al., Coactivator TIF1? Interacts with Transcription Factor C/EBP? and Glucocorticoid Receptor To Induce ?1-Acid Glycoprotein Gene Expression. Mol. Cell. Biol., 18(10), 5880-5887 (1998).
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