CASP9
caspase 9, apoptosis-related cysteine peptidase
Sinónimos:
APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56
Especie:
Human CASP9 (842), Mouse Casp9 (12371), Rat Casp9 (58918), domestic cat CASP9 (768260), naked mole-rat Casp9 (101702898), cow CASP9 (100140945), Horse CASP9 (100054331), dog CASP9 (487432), chicken CASP9 (426970), sheep CASP9 (101110953) ...Más
ID UniProtKB:
ID del gen:
- Human(842) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
- Mouse(12371) caspase 9
- Rat(58918) caspase 9, apoptosis-related cysteine peptidase
- domestic cat(768260) caspase 9, apoptosis-related cysteine peptidase
- naked mole-rat(101702898) caspase 9, apoptosis-related cysteine peptidase
- cow(100140945) caspase 9, apoptosis-related cysteine peptidase
- Horse(100054331) caspase 9, apoptosis-related cysteine peptidase
- dog(487432) caspase 9, apoptosis-related cysteine peptidase
- chicken(426970) caspase 9, apoptosis-related cysteine peptidase
- sheep(101110953) caspase 9, apoptosis-related cysteine peptidase
- domestic guinea pig(100714954) caspase 9, apoptosis-related cysteine peptidase
- Zebrafish(492763) caspase 9, apoptosis-related cysteine protease
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-Caspase 9 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
western blot
Anti-Caspase-9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Caspase 9 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Caspase-9 Antibody, clone 1G22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-CASP9 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
esiRNA
Small Molecule - Substrate
Número de producto
Descripción
Especie
N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin, ≥95% (HPLC), powder,
Especie
mouse, rat, human