95212

L-Ascorbic acid

tested according to Ph. Eur.

• Synonym(s): Acidum ascorbicum, L-Threoascorbic acid, Antiscorbutic factor, Vitamin C
• Empirical Formula (Hill Notation): C₆H₈O₆
• CAS Number: 50-81-7
• Molecular Weight: 176.12
• UNSPSC Code: 12352205
• NACRES: NA.21
• PubChem Substance ID: 329770428
• EC Number: 200-066-2
• Beilstein/REAXYS Number: 84272
• MDL number: MFCD00064328

Properties

• InChI key: CIWBSHSKHKDKBQ-JLAZNSOCSA-N
• InChI: 1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
• SMILES string: OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
• biological source: synthetic
• Gene Information: human ... SLC23A2(9962)
• agency: tested according to Ph. Eur.
• assay: 99.0-100.5%
• form: solid
• color: white to off-white
• pH: 1.0-2.5 (25 °C, 176 g/L in water)
• mp: 190-194 °C (dec.)
• solubility: water: soluble 176 g/L at 20 °C
• Quality Level: 200

Description

General description

L-Ascorbic acid is the most biologically active form of ascorbic acid. It is hydrophilic and an unstable compound.[1] L-Ascorbic acid contains a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid, also referred to as Vitamin C, is a water-soluble vitamin.[2] Ascorbic acid carries a neutral charge, which gets converted to ascorbate by protonation.[3] Vitamin C is a part of citrus fruits, such as broccoli, strawberries, turnip.[2]

Application

• Targeted screening of multiple anti-inflammatory components from Chrysanthemi indici Flos by ligand fishing with affinity UF-LC/MS: This study investigates the application of L-Ascorbic acid in enhancing the screening of anti-inflammatory compounds, utilizing its properties to stabilize reactive samples in cell cultures (Huang et al., 2024).


• Phenolic Content, Antioxidant Potential, and Antimicrobial Activity of Uvaria chamae (Annonaceae), a Food Plant from Burkina Faso: Demonstrates the use of L-Ascorbic acid in the evaluation of antioxidant properties of plant extracts, which is crucial in the pharmaceutical research of natural products (Kabore et al., 2024).

Biochem/physiol Actions

_L-Ascorbic acid functions according to its oxido-reduction property. It is a co-factor for hydroxylation. The biochemical actions of L-ascorbic acid is dependent on the activity of monoxygenase. It is involved in carnitine, collagen synthesis and production of neurotransmitters.[2] Vitamin C exhibits anti-oxidant properties. Vitamin C plays a role in providing protection against photoaging and anti-aging effect.[1] Deficiency of vitamin C leads to scurvy, bleeding gums, poor wound healing, anemia and muscle degeneration.[2]

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)