The storage temperature and solution stability after reconstitution in DMSO have not been tested. It is recommended to make the solution fresh upon usage.
P1793
Pimozide
≥98% (TLC), powder, D₂ dopamine receptor antagonist
Synonym(s):
1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
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500 MG
$114.00
1 G
$202.00
About This Item
Empirical Formula (Hill Notation):
C28H29F2N3O
CAS Number:
Molecular Weight:
461.55
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
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Product Name
Pimozide,
form
powder
Quality Level
solubility
DMSO: 18 mg/mL(lit.)
chloroform: 5 mg/mL
H2O: insoluble(lit.)
originator
Teva
storage temp.
2-8°C
SMILES string
Fc1ccc(cc1)C(CCCN2CCC(CC2)N3C(=O)Nc4ccccc34)c5ccc(F)cc5
InChI
1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)
InChI key
YVUQSNJEYSNKRX-UHFFFAOYSA-N
Gene Information
human ... ABCB1(5243), CACNA1G(8913), CYP3A4(1576), DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816), HTR2A(3356), HTR7(3363), KCNH1(3756), KCNH2(3757), OPRD1(4985)
mouse ... Abcb1a(18671), Abcb1b(18669)
rat ... Scnn1g(24768)
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This Item | BP682 | P-168 | Y0002391 |
|---|---|---|---|
| form powder | form solid | form - | form - |
| Quality Level 200 | Quality Level - | Quality Level 300 | Quality Level - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. -10 to -25°C | storage temp. 2-8°C |
| solubility DMSO: 18 mg/mL(lit.), H2O: insoluble(lit.), chloroform: 5 mg/mL | solubility - | solubility - | solubility - |
| originator Teva | originator - | originator - | originator - |
| Gene Information human ... ABCB1(5243), CACNA1G(8913), CYP3A4(1576), DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816), HTR2A(3356), HTR7(3363), KCNH1(3756), KCNH2(3757), OPRD1(4985) | Gene Information human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816), HTR2A(3356) | Gene Information - | Gene Information - |
Biochem/physiol Actions
D2 dopamine receptor antagonist; binds with high affinity to the cloned 5-HT7 receptor; Ca2+ channel antagonist; antipsychotic
Features and Benefits
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Cyclic Nucleotide-Gated (CNG) and Hyperpolarization Activated Cyclic Nucleotide-Gated (HCN) Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Teva. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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