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Merck

49449

L-グルタミン酸

≥99.5% (NT), BioUltra

別名:

(S)-2-アミノペンタン二酸, Glu

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サイズを選択してください

100 G

¥8,580

500 G

¥17,270

¥8,580

単価¥15,600割引45%

在庫あり出荷可能詳細


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この商品について

化学式:
HO2CCH2CH2CH(NH2)CO2H
CAS番号:
分子量:
147.13
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-293-7
MDL number:
Beilstein/REAXYS Number:
1723801

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製品名

L-グルタミン酸, BioUltra, ≥99.5% (NT)

SMILES string

N[C@@H](CCC(O)=O)C(O)=O

InChI key

WHUUTDBJXJRKMK-VKHMYHEASA-N

InChI

1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1

product line

BioUltra

assay

≥99.5% (NT)

form

powder

optical activity

[α]20/D +31.5±1.0°, c = 5% in 5 M HCl

impurities

insoluble matter, passes filter test
≤0.5% foreign amino acids

ign. residue

≤0.05% (as SO4)

loss

≤0.05% loss on drying, 20 °C (HV)

color

white

mp

205 °C (dec.) (lit.)

solubility

1 M HCl: 1 M at 20 °C, clear, colorless

density

1.54 g/cm3 at 20 °C

anion traces

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤200 mg/kg

cation traces

Al: ≤5 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤200 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
NH4+: ≤100 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in 1 M HCl

UV absorption

λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.1

application(s)

cell analysis

Quality Level

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当該品目
W32850212-0880PHR1107
form

powder

form

powder or crystals

form

crystalline

form

-

assay

≥99.5% (NT)

assay

98.5-101.5% dry basis (perchloric acid titration)

assay

≥99.0%

assay

-

product line

BioUltra

product line

-

product line

-

product line

-

mp

205 °C (dec.) (lit.)

mp

205 °C (dec.) (lit.)

mp

205 °C (dec.) (lit.)

mp

205 °C (dec.) (lit.)

optical activity

[α]20/D +31.5±1.0°, c = 5% in 5 M HCl

optical activity

[α]20/D +32°, c = 10 in 2 M HCl

optical activity

-

optical activity

-

cation traces

Al: ≤5 mg/kg, Bi: ≤5 mg/kg, Cd: ≤5 mg/kg, Cr: ≤5 mg/kg, Fe: ≤5 mg/kg, Li: ≤5 mg/kg, Mn: ≤5 mg/kg, NH4+: ≤100 mg/kg, Ni: ≤5 mg/kg, Sr: ≤5 mg/kg, Ba: ≤5 mg/kg, Co: ≤5 mg/kg, K: ≤50 mg/kg, Mo: ≤5 mg/kg, Pb: ≤5 mg/kg, Ca: ≤200 mg/kg, Mg: ≤5 mg/kg, Zn: ≤5 mg/kg, Cu: ≤5 mg/kg, Na: ≤200 mg/kg

cation traces

As: ≤3 ppm, Cd: ≤1 ppm, Hg: ≤1 ppm, Pb: ≤5 ppm

cation traces

-

cation traces

-

Biochem/physiol Actions

興奮性アミノ酸系伝達物質で、グルタミン酸受容体(代謝型受容体、カイニン酸受容体、NMDA受容体、AMPA受容体)のあらゆるサブタイプのアゴニストです。

Other Notes

興奮毒性を持つLesion-sparing agentです。[1]タンパク質の結晶化では沈殿剤として機能します。[2]各種微生物の増殖に必要な成分です。[3]

保管分類

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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CRC Handbook of Microbiology, 4, 1-1 (1974)
Excitotoxic amino acids as neuroendocrine research tools.
J W Olney et al.
Methods in enzymology, 103, 379-393 (1983-01-01)
Protein crystallization: the growth of large-scale single crystals.
G L Gilliland et al.
Methods in enzymology, 104, 370-381 (1984-01-01)
Luigi F Agnati et al.
Pharmacological reviews, 55(3), 509-550 (2003-07-19)
The molecular basis for the known intramembrane receptor/receptor interactions among G protein-coupled receptors was postulated to be heteromerization based on receptor subtype-specific interactions between different types of receptor homomers. The discovery of GABAB heterodimers started this field rapidly followed by
Kimberly J Dougherty et al.
Neuron, 80(4), 920-933 (2013-11-26)
Locomotion is controlled by spinal networks that generate rhythm and coordinate left-right and flexor-extensor patterning. Defined populations of spinal interneurons have been linked to patterning circuits; however, neurons comprising the rhythm-generating kernel have remained elusive. Here, we identify an ipsilaterally

質問

1–2/2 質問  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 回答
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 回答
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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