MAP2K1
mitogen-activated protein kinase kinase 1
同義詞:
CFC3, MAPKK1, MEK1, MKK1, PRKMK1
物種:
Human MAP2K1 (5604), Mouse Map2k1 (26395), Rat Map2k1 (170851), domestic guinea pig Map2k1 (100712888), dog MAP2K1 (478347), Horse MAP2K1 (100065996), domestic cat MAP2K1 (101081387), chicken MAP2K1 (415549), naked mole-rat Map2k1 (101715628), cow MAP2K1 (533199) ...更多
UniProtKB ID:
基因 ID:
- Human(5604) Summary: The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]
- Mouse(26395) mitogen-activated protein kinase kinase 1
- Rat(170851) mitogen activated protein kinase kinase 1
- domestic guinea pig(100712888) mitogen-activated protein kinase kinase 1
- dog(478347) mitogen-activated protein kinase kinase 1
- Horse(100065996) mitogen-activated protein kinase kinase 1
- domestic cat(101081387) mitogen-activated protein kinase kinase 1
- chicken(415549) mitogen-activated protein kinase kinase 1
- naked mole-rat(101715628) mitogen-activated protein kinase kinase 1
- cow(533199) mitogen-activated protein kinase kinase 1
- Domestic Rabbit(100009316) mitogen-activated protein kinase kinase 1
- sheep(101123635) mitogen-activated protein kinase kinase 1
- Zebrafish(406728) mitogen-activated protein kinase kinase 1
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Antibodies
產品編號
描述
物種活性
應用
抗磷酸化MEK1（Ser218/222）/MEK2（Ser222/226）抗体（兔单克隆）, Upstate®, from rabbit,
物種活性
human, mouse, rat
應用
western blot
MAPK Pathway 1 Explorer Antibody MiniPack, clone AW39R, 1 mg/mL (05-538SP), Upstate®,
物種活性
xenopus, chicken, human, mouse, rat
應用
activity assay
flow cytometry
immunofluorescence
multiplexing
western blot
flow cytometry
immunofluorescence
multiplexing
western blot
Anti-MAP Kinase Kinase (MEK, MAPKK) antibody produced in rabbit, whole antiserum,
物種活性
human, mouse, rat
應用
microarray
western blot
western blot
Small Molecule - Inhibitor
產品編號
描述
物種
U0126, U0126 is a elective inhibitor of MEK-1 and MEK-2; weak inhibitor of PKC, Raf, ERK, JNK, MEKK, MKK-3, MKK-4/SEK, MKK-6, Abl, Cdk2 and Cdk4.,
物種
human
Proteins
產品編號
描述
物種
MEK1蛋白，失活，50 g, Unactive, N-terminal GST & C-terminal His6-tagged, recombinant full-length human MEK1, for use in Kinase Assays.,
物種
human
MEK1 Protein, active, 10 µg, Active, N-terminal GST & C-terminal His6-tagged, recombinant full-length human MEK1, for use in Kinase Assays.,
物種
human
MEK1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
mouse