STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
同義詞:
APRF, HIES
物種:
Human STAT3 (6774), Mouse Stat3 (20848), Rat Stat3 (25125), naked mole-rat Stat3 (101721899), domestic guinea pig Stat3 (100717084), chicken STAT3 (420027), Zebrafish stat3 (30767), sheep STAT3 (100294659), domestic cat STAT3 (101095698), cow STAT3 (508541) ...更多
UniProtKB ID:
基因 ID:
- Human(6774) Summary: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(20848) signal transducer and activator of transcription 3
- Rat(25125) signal transducer and activator of transcription 3 (acute-phase response factor)
- naked mole-rat(101721899) signal transducer and activator of transcription 3 (acute-phase response factor)
- domestic guinea pig(100717084) signal transducer and activator of transcription 3 (acute-phase response factor)
- chicken(420027) signal transducer and activator of transcription 3 (acute-phase response factor)
- Zebrafish(30767) signal transduction and activation of transcription 3
- sheep(100294659) signal transducer and activator of transcription 3 (acute-phase response factor)
- domestic cat(101095698) signal transducer and activator of transcription 3 (acute-phase response factor)
- cow(508541) signal transducer and activator of transcription 3 (acute-phase response factor)
- Horse(100052852) signal transducer and activator of transcription 3 (acute-phase response factor)
- Domestic Rabbit(100348778) signal transducer and activator of transcription 3 (acute-phase response factor)
- dog(490967) signal transducer and activator of transcription 3 (acute-phase response factor)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Antibodies
產品編號
描述
物種活性
應用
抗磷酸化STAT3（Tyr705）抗体，克隆9E12, clone 9E12, Upstate®, from mouse,
物種活性
canine, human, mouse
應用
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
抗 磷酸化-STAT3 (pTyr 705 ) 兔抗, affinity isolated antibody,
物種活性
human, mouse, rat
應用
immunohistochemistry
western blot
western blot
Anti-Phospho-STAT3 (Tyr705) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM261, purified immunoglobulin,
物種活性
human
應用
immunohistochemistry
western blot
western blot
Anti-Stat3 Antibody, from rabbit,
物種活性
bovine, human, mouse, pig, porcine, primate, rat
應用
immunoprecipitation (IP)
western blot
western blot
抗-磷酸STAT3 (pSer727) 兔抗, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot