46746
Polyglycolic acid
Synonym(s):
PGA, Poly(2-hydroxyacetic acid)
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description
inherent viscosity 1.2 dl/g
InChI
1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
Inchi Key
AEMRFAOFKBGASW-UHFFFAOYSA-N
Application
medical device
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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M A Tiunin et al.
Eksperimental'naia i klinicheskaia farmakologiia, 76(1), 3-6 (2013-03-07)
Technological parameters for the effective encapsulation of n-(1-phenethyl-4-piperidyl)propionanilide in poly(lactid-co-glycolide) (PLG) nanoparticles have been determined. Depending on the ratio of drug fractions adsorbed on the particle surface and associated with the polymer matrix, n-(1-phenethyl-4-piperidyl)propionanilide (200 microg/kg, i/m) loaded PLG nanospheres
Huaping Chen et al.
Biomaterials, 34(16), 4159-4172 (2013-03-14)
The absence of safe, efficient, cost-effective, and easily scalable delivery platforms is one of the most significant hurdles and critical issues that limit the bench to bedside translation of oligonucleotides-based therapeutics. Acid-labile materials are of special interest in developing nonviral
Rodney A Rosalia et al.
Cancer immunology, immunotherapy : CII, 62(7), 1161-1173 (2013-04-25)
Protein antigen (Ag)-based immunotherapies have the advantage to induce T cells with a potentially broad repertoire of specificities. However, soluble protein Ag is generally poorly cross-presented in MHC class I molecules and not efficient in inducing robust cytotoxic CD8(+) T
Steven Lotz et al.
PloS one, 8(2), e56289-e56289 (2013-02-26)
An essential aspect of stem cell culture is the successful maintenance of the undifferentiated state. Many types of stem cells are FGF2 dependent, and pluripotent stem cells are maintained by replacing FGF2-containing media daily, while tissue-specific stem cells are typically
Mitsuhiro Enjo et al.
Plastic and reconstructive surgery, 131(3), 335e-342e (2013-03-01)
Approaches to auricular reconstruction have shown improved outcome when a basic fibroblast growth factor (bFGF) slow-release system and fibrin spraying are combined with biodegradable polymers. More complex, three-dimensional structures, such as those that replicate the human auricle, are often lost
Articles
Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.
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