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Oxymatrine

Name: Oxymatrine
Brand: SIGMA

About This Item

Empirical Formula (Hill Notation):

C₁₅H₂₄N₂O₂

CAS Number:

16837-52-8

Molecular Weight:

264.36

NACRES:

NA.25

PubChem Substance ID:

329818891

UNSPSC Code:

12352200

MDL number:

MFCD00210339

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Properties

assay

≥98% (HPLC)

Quality Level

100

form

powder

solubility

methanol: 10 mg/mL, clear, colorless

storage temp.

2-8°C

SMILES string

[O-][N+]12CCCC3CN4C(CCCC4=O)C(CCC1)C23

InChI

1S/C15H24N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-,17?/m0/s1

InChI key

XVPBINOPNYFXID-LHDUFFHYSA-N

Description

Biochem/physiol Actions

Alkaloid isolated from Sophora flavescens. Antifribotic. Neuroprotective. Traditional chinese medicine used in the treatment against hepatitis B virus.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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An integrated characterization of contractile, electrophysiological, and structural cardiotoxicity of Sophora tonkinensis Gapnep. in human pluripotent stem cell-derived cardiomyocytes.

Ruiying Wang et al.

Stem cell research & therapy, 10(1), 20-20 (2019-01-13)

Cardiotoxicity remains an important concern in drug discovery and clinical medication. Meanwhile, Sophora tonkinensis Gapnep. (S. tonkinensis) held great value in the clinical application of traditional Chinese medicine, but cardiotoxic effects were reported, with matrine, oxymatrine, cytisine, and sophocarpine being

The protective role of oxymatrine on neuronal cell apoptosis in the hemorrhagic rat brain.

Man Huang et al.

Journal of ethnopharmacology, 143(1), 228-235 (2012-07-04)

Oxymatrine is extracted from the traditional Chinese herb Sophora flavescens Ait, possesses anti-inflammatory, anti-oxidative and anti-apoptotic properties, and has been used for the treatment of chronic viral hepatitis and many other diseases. This study aimed to investigate the effects of

The synergistic anti-inflammatory effect of the combination of sodium ferulate and oxymatrine and its modulation on inflammation-associated mediators in RAW 264.7 cells.

Xiaopei Yuan et al.

Journal of ethnopharmacology, 137(3), 1477-1485 (2011-09-01)

The combination of Radix Angelicae sinensis (Oliv.) Diels and Radix Sophora flavescens Ait. was extensively used in traditional Chinese medicine to treat inflammatory diseases, such as acne, heart disease, and hepatitis. Sodium ferulate (SF) and oxymatrine (OMT) were effective component

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Global Trade Item Number

SKU	GTIN
O0891-10MG	04061832402000

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