Connection/Disconnection for Bioprocessing
Sterilized fluid transfer systems containing tubing, connectors, clamps, valves, and disconnectors provide a critical link between disposable fluid paths and the various steps in your aseptic process, whether that is plastic-to-stainless or plastic-to-plastic. We offer three types of connectors and a crimping tool for sterile disconnection. We also can configure standard single-use assemblies with common types of commercially available tubing, such as platinum-cured silicone and C-Flex® 374 thermoplastic elastomer.
Reliable and easy to use, Lynx® connectors feature unique designs that enable fluid transfer and maintain sterility. Lynx® connectors are available separately or as part of a complete assembly.
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Products
Lynx® CDR (Connect, Disconnect, and Reconnect) Connector
Lynx® CDR Connector provides a reliable and validated connection for multiple transfers of sterile fluids. It is designed to provide flexibility in single-use bioprocessing by enabling up to six connections, disconnections, and reconnections of multiple flow paths while remaining sterile and leak-free. The Lynx® CDR Sterile Connector is available in a wide range of sizes, from 3/8- inch hose barb to 1½-inch TC, and configurations from sampling to intermediate additions to bulk liquid transfer. Connect, disconnect, and reconnect your single-use and hybrid systems both wet and under pressure.
Lynx® ST (Steam-To) Connector
Lynx® ST Connector lets you integrate steamable hard-piped process equipment with disposable sterile fluid paths. Available in ¼-inch, ½-inch, and 1-inch sizes, the Lynx® ST Connector provides an economical, easy, and reliable sterile connection for the secure transfer or sampling of sterile fluids. Lynx® ST Connector is gamma- and autoclave-compatible, making it ideal for integration into sterilized assemblies.
Sterile disconnection
NovaSeal™ Crimping Tool securely seals and disconnects a single-use assembly into two sterile fluid paths. Available in manual and battery-powered format, the tool crimps and cuts a pinch-pipe and silicone tube at the same time in one simple motion. This pinch-pipe/tube combination and crimping tool provides you with a sterile means to cut and separate your Mobius® assembly, maintain sterility, and securely protect the fluid from the outside environment.
Related Videos
Related Product Resources
- Tech Brief: Holistic Buffer Preparation
A holistic buffer management overview
- Tech Brief: Steam-In-Place Feasibility Study for Lynx® CDR 1.5-inch Female Sterile-to-Sterile Connectors
Describes the mechanical strength of Lynx® CDR connectors during extreme steaming conditions as well as their ability to be steam sterilized.
- Tech Brief: Lynx® S2S and Lynx® ST Connector Tubing Assembly Autoclave Sterilization
This study was designed to determine the minimum time required to achieve sterilization of different assemblies containing tubing, filters, and Lynx® S2S connectors using both gender couplings and Lynx® ST connectors.
- Tech Brief: Lynx® S2S Connector Capability and Integrity after Three Autoclave Sterilization
This technical brief summarizes data demonstrating the integrity and functionality of Lynx® S2S connectors after exposure to aggressive autoclave sterilization conditions.
- Data Sheet: Lynx® CDR Connector
The Lynx® CDR (Connect, Disconnect and Reconnect) device provides a reliable and validated connection for multiple transfers of sterile fluids.
- Data Sheet: Lynx® S2S Connector
The uniquely designed Lynx® S2S (sterile to sterile) connector is a single-use, single-actuation, gamma and autoclave compatible disposable device for connecting sterilized fluid paths in biopharmaceutical processes.
- Data Sheet: Lynx® ST Connector
Enables integration of steamable hard piped process equipment with disposable sterile fluid paths
- Data Sheet: NovaSeal™ Crimping Tool
Securely seal and separate single-use tubing
- Application Note: Implementation of Lynx® CDR Sterile Connectors in a Perfusion Application
This two-tiered study was designed to explore both how the connector may contribute to cell shear in flow rate conditions similar to those observed in typical 200 L perfusion bioprocesses, and also to demonstrate the efficacy of implementing a Lynx® CDR connector in an actual perfusion process using an XCell™ ATF 2 System.
- Application Note: Use of the Lynx® CDR Connector in a Non-classified “Gray Space” Environment
In this study, the Lynx® CDR Connector was utilized during two typical bioprocessing steps (media preparation and bioreactor fill) where multiple connections/disconnections are required.
- Tech Brief: Choosing the right sterile connector based on design and sterility test results
Factors to consider when choosing a single-use connector
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