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Merck

FLNA

filamin A, alpha

別名:
ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2316) Summary: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
  • Mouse(192176) filamin, alpha
  • Rat(293860) filamin A, alpha
  • domestic guinea pig(100725162) filamin A, alpha
  • Zebrafish(562529) filamin A, alpha (actin binding protein 280)
  • chicken(395261) filamin A, alpha
  • naked mole-rat(101702004) filamin A, alpha
  • Zebrafish(100534866) filamin A, alpha
  • sheep(101120390) filamin A, alpha
  • dog(481084) filamin A, alpha
  • Domestic Rabbit(100328754) filamin A, alpha
  • cow(281165) filamin A, alpha
  • domestic cat(101082637) filamin A, alpha

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
抗FLNA ウサギ宿主抗体, Ab3, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti-Filamin A Antibody, clone TI10, Ascites Free, clone TI10, 1 mg/mL, from mouse,
交差性
bovine, human
アプリケーション
flow cytometry
immunocytochemistry

immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Filamin A Antibody, clone TI10, ascites fluid, clone TI10, Chemicon®,
交差性
bovine, human
アプリケーション
immunohistochemistry
immunoprecipitation (IP)

western blot
抗FLNA ウサギ宿主抗体, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
western blot
抗-フィラミン抗体、マウスモノクローナル, clone PM6/317, purified from hybridoma cell culture,
交差性
bovine, canine, hamster, human, monkey
アプリケーション
immunofluorescence
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human FLNA,
Species
human