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Merck

PYCARD

PYD and CARD domain containing

別名:
ASC, CARD5, TMS, TMS-1, TMS1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(29108) Summary: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(66824) PYD and CARD domain containing
  • Rat(282817) PYD and CARD domain containing
  • Goat(100861338) PYD and CARD domain containing
  • domestic guinea pig(100734858) PYD and CARD domain containing
  • domestic cat(101088449) PYD and CARD domain containing
  • sheep(101105208) PYD and CARD domain containing
  • dog(489925) PYD and CARD domain containing
  • Zebrafish(57923) PYD and CARD domain containing
  • cow(282846) PYD and CARD domain containing

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-ASC Antibody, clone 2EI-7, clone 2EI-7, from mouse,
交差性
human, mouse
アプリケーション
flow cytometry
western blot
Anti-ASC antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry

western blot
Anti-ASC/TMS1 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
western blot
抗PYCARD抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
抗ASC ウサギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunocytochemistry

immunohistochemistry

western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PYCARD,
Species
human