166375
Formic hydrazide
Synonym(s):
Formic acid hydrazide, Formylhydrazine
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About This Item
Linear Formula:
HCONHNH2
CAS Number:
Molecular Weight:
60.06
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-867-9
Beilstein/REAXYS Number:
635759
MDL number:
Pricing and availability is not currently available.
Quality Level
mp
52-57 °C (lit.)
solubility
water: soluble 2.5%, clear, colorless
functional group
amine, hydrazine
SMILES string
[H]C(=O)NN
InChI
1S/CH4N2O/c2-3-1-4/h1H,2H2,(H,3,4)
InChI key
XZBIXDPGRMLSTC-UHFFFAOYSA-N
Application
Formic hydrazide was used in the synthesis of 1,2,4-triazole derivatives. It was also used in the synthesis of new anticancer agent, 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(β-D-glucopyranosyl)-5H-indolo[2,3-a]-pyrrolo[3,4-c]carbazole-5,7(6H)-dione.
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This Item | |||
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| solubility water: soluble 2.5%, clear, colorless | solubility H2O: soluble 50 mg/mL | solubility - | solubility - |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| mp 52-57 °C (lit.) | mp 159-161 °C (lit.) | mp 77-79 °C (lit.) | mp - |
| functional group amine, hydrazine | functional group amine, hydrazine | functional group amine, hydrazine | functional group amine, hydrazine |
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
233.6 °F - closed cup
flash_point_c
112 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
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B Toth et al.
Carcinogenesis, 1(1), 61-65 (1980-01-01)
N-ethyl-N-formylhydrazine (EFH) was administered as a 0.02% solution in drinking water continuously for life to randomly bred Swiss mice, from 6 weeks of age. The treatment induced tumors of the lungs, blood vessels, liver, gall bladder and preputial glands. The
Traceless liquid-phase synthesis of 3-alkylamino-4, 5-disubstituted-1, 2, 4-triazoles on polyethylene glycol (PEG).
Zong Y-X, et al.
Tetrahedron Letters, 46(31), 5139-5141 (2005)
Synthesis of NB-506, a new anticancer agent.
Ohkubo M, et al.
Tetrahedron, 53(2), 585-592 (1997)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P8791-100MG | 04061832780771 |
| 166375-100G | 04061831818895 |
| 166375-25G | 04061831818901 |