D4635
2′-Deoxycytidine 5′-triphosphate disodium salt
≥95%
Synonym(s):
dCTP-Na2
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 mg | Check Cart for Availability | RM 522.00 | |
| 25 mg | Check Cart for Availability | RM 1,157.00 | |
| 100 mg | Check Cart for Availability | RM 3,405.00 | |
| 1 g | Check Cart for Availability | RM 16,284.00 |
About This Item
Empirical Formula (Hill Notation):
C9H14N3Na2O13P3
CAS Number:
Molecular Weight:
511.12
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Assay:
≥95%
Form:
powder
Storage temp.:
−20°C
RM 522.00
Check Cart for Availability
Quality Level
assay
≥95%
form
powder
shipped in
dry ice
storage temp.
−20°C
SMILES string
[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)O2
InChI
1S/C9H16N3O13P3.2Na/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17;;/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17);;/q;2*+1/p-2/t5-,6+,8+;;/m0../s1
InChI key
ABWVCNMFYVEBIB-CDNBRZBRSA-L
General description
2′-Deoxycytidine 5′-triphosphate (dCTP) is synthesized either by de novo pathway or from the multiple phosphorylation steps of cytidine. It is deaminated to deoxyuridine monophosphate (dUMP) which is convertible to deoxythymidine triphosphate (dTTP).
Application
2′-Deoxycytidine 5′-triphosphate disodium salt has been used:
- in polymerase chain reaction mix for the amplification of Alternaria (AM) toxin DNA[1]
- to spike oligonucleotide sample for capillary electrophoresis (CE) analysis[2]
- as a component in adenosine 5′-monophosphate (AMP) luciferase assay[3]
2′-Deoxycytidine 5′-triphosphate disodium salt is one of the nucleoside triphosphates used for DNA polymerase driven reactions such as polymerase chain reaction, DNA sequencing and other molecular biology methods.
Biochem/physiol Actions
2′-Deoxycytidine 5′-triphosphate (dCTP) is used to synthesize DNA by DNA polymerases or reverse transcriptases. dCTP is an allosteric regulator of deoxycytidylate (dCMP) deaminase.[4] It is used in studies of nucleotide pools, nucleotide selectivity and enzyme specificity studies, such as the preferred incorporation of dCTP by Rev1, a γ-family DNA polymerase.[5]
1 of 1
This Item | |||
|---|---|---|---|
| Quality Level 200 | Quality Level 200 | Quality Level - | Quality Level 200 |
| form powder | form liquid | form solution | form liquid |
| assay ≥95% | assay ≥99% | assay 99% (dNTP) | assay ≥99% |
| shipped in dry ice | shipped in dry ice | shipped in - | shipped in dry ice |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
Still not finding the right product?
Explore all of our products under 2′-Deoxycytidine 5′-triphosphate disodium salt
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Paola Ferraro et al.
Nucleic acids research, 38(6), e85-e85 (2009-12-17)
Eukaryotic cells contain a delicate balance of minute amounts of the four deoxyribonucleoside triphosphates (dNTPs), sufficient only for a few minutes of DNA replication. Both a deficiency and a surplus of a single dNTP may result in increased mutation rates
Xiaoli Xiang et al.
Analytical biochemistry, 460, 22-28 (2014-05-27)
A luciferase-based method was developed for measurement of 5'-adenylylsulfate (APS) reductase (APR), an enzyme of the reductive sulfate assimilation pathway in prokaryotes and plants. APR catalyzes the two-electron reduction of APS and forms sulfite and adenosine 5'-monophospahate (AMP). The luciferase-based
Genetics: Analysis of Genes and Genomes (2009)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| D4635-25MG | 04061833006887 |
| D4635-1G | 04061826690567 |
| D4635-100MG | 04061833565575 |
| D4635-10MG | 04061833006870 |