FANCD2
Fanconi anemia, complementation group D2
Sinônimos:
FA-D2, FA4, FACD, FAD, FAD2, FANCD
Espécies:
Human FANCD2 (2177), Mouse Fancd2 (211651), Rat Fancd2 (312641), dog FANCD2 (484659), Horse FANCD2 (100051871), naked mole-rat Fancd2 (101705946), cow FANCD2 (515845), chicken FANCD2 (415935), Zebrafish fancd2 (394241), domestic guinea pig Fancd2 (100729511) ...Mais
ID UniProtKB:
ID do gene:
- Human(2177) Summary: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(211651) Fanconi anemia, complementation group D2
- Rat(312641) Fanconi anemia, complementation group D2
- dog(484659) Fanconi anemia, complementation group D2
- Horse(100051871) Fanconi anemia, complementation group D2
- naked mole-rat(101705946) Fanconi anemia, complementation group D2
- cow(515845) Fanconi anemia, complementation group D2
- chicken(415935) Fanconi anemia, complementation group D2
- Zebrafish(394241) Fanconi anemia, complementation group D2
- domestic guinea pig(100729511) Fanconi anemia, complementation group D2
- fruit fly(2768674) CG17269 gene product from transcript CG17269-RA
- Domestic Rabbit(100346581) Fanconi anemia, complementation group D2
- domestic cat(101092341) Fanconi anemia, complementation group D2
- sheep(101123503) Fanconi anemia, complementation group D2
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Antibodies
Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-FANCD2 Antibody, clone 10F8.1, clone 10F8.1, from mouse,
Reatividade de espécies
human
Aplicação
immunohistochemistry
western blot
western blot
Anti-FANCD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reatividade de espécies
human
Aplicação
immunofluorescence
Anti-phospho-FANCD2 (pSer222) antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Rabbit anti-FANCD2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Reatividade de espécies
human
Aplicação
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-FANCD2 Antibody, clone 7U2D6, Rabbit Monoclonal, ,
Reatividade de espécies
human, rat
Aplicação
western blot