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Merck

CDKN1B

cyclin-dependent kinase inhibitor 1B (p27, Kip1)

別名:
CDKN4, KIP1, MEN1B, MEN4, P27KIP1
Species:
Human CDKN1B (1027), Mouse Cdkn1b (12576), Rat Cdkn1b (83571), chicken CDKN1B (769872), chicken CDKN1B (374106), dog CDKN1B (403429), domestic cat CDKN1B (493958), Domestic Rabbit CDKN1B (100009037), cow CDKN1B (512613), sheep CDKN1B (100127219) ...詳細
UniProtKB ID:
P46527, Q16307, Q5U0H2, Q9BUS6
遺伝子ID:
  • Human(1027) Summary: This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq, Jul 2008]
  • Mouse(12576) cyclin-dependent kinase inhibitor 1B
  • Rat(83571) cyclin-dependent kinase inhibitor 1B
  • chicken(769872) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • chicken(374106) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • dog(403429) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • domestic cat(493958) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • Domestic Rabbit(100009037) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • cow(512613) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • sheep(100127219) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • naked mole-rat(101698721) cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • domestic guinea pig(100729359) cyclin-dependent kinase inhibitor 1B (p27, Kip1)

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Antibodies

製品番号
詳細
交差性
アプリケーション
SAB4504200
Anti-phospho-p27 Kip1 (pThr198) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot
SAB4500068
Anti-p27 KIP1 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry
western blot
06-445
Anti-Kip1 (p27) Antibody, Upstate®, from rabbit,
交差性
human, rabbit, rat
アプリケーション
immunohistochemistry
immunoprecipitation (IP)
western blot
WH0001027M1
Monoclonal Anti-CDKN1B antibody produced in mouse, clone 4B4-E6, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
HPA059086
抗CDKN1B抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
R7772
ロスコビチン, ≥98% (TLC),
Species
human, mouse, rat
O0886
オロモウシン, ≥98% (HPLC),
Species
human, rat

Proteins

製品番号
詳細
Species
23-024-M
p27 Protein complex, activated, 10 µg, Activated complex of three (3) full length, recombinant human proteins: p27, Cyclin E1, & CDK2. Phosphorylated in vitro using CDK2/Cyclin E1. For use in Enzyme Assays. Behaves as a substrate in ubiquitin assays.,
Species
human

esiRNA

製品番号
詳細
Species
EHU025821
MISSION® esiRNA, targeting human CDKN1B,
Species
human
EMU028461
MISSION® esiRNA, targeting mouse Cdkn1b,
Species
mouse