PDE4B
phosphodiesterase 4B, cAMP-specific
別名:
DPDE4, PDE4B5, PDEIVB
Species:
Human PDE4B (5142), Mouse Pde4b (18578), Rat Pde4b (24626), naked mole-rat Pde4b (101703441), domestic guinea pig Pde4b (100720296), chicken PDE4B (424700), domestic cat PDE4B (101081316), dog PDE4B (479540), cow PDE4B (100124505), Horse PDE4B (100053961) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(5142) Summary: This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
- Mouse(18578) phosphodiesterase 4B, cAMP specific
- Rat(24626) phosphodiesterase 4B, cAMP specific
- naked mole-rat(101703441) phosphodiesterase 4B, cAMP-specific
- domestic guinea pig(100720296) phosphodiesterase 4B, cAMP-specific
- chicken(424700) phosphodiesterase 4B, cAMP-specific
- domestic cat(101081316) phosphodiesterase 4B, cAMP-specific
- dog(479540) phosphodiesterase 4B, cAMP-specific
- cow(100124505) phosphodiesterase 4B, cAMP-specific
- Horse(100053961) phosphodiesterase 4B, cAMP-specific
- Domestic Rabbit(100355058) phosphodiesterase 4B, cAMP-specific
- sheep(101111757) phosphodiesterase 4B, cAMP-specific
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Small Molecule - Antagonist
製品番号
詳細
Species
Antibodies
製品番号
詳細
交差性
アプリケーション
抗PDE4B抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-PDE4B2 Antibody, from rabbit, purified by affinity chromatography,
交差性
human, rat
アプリケーション
western blot
抗PDE4B抗体 クローン1E9 ZooMAb®ウサギモノクローナル, recombinant, expressed in HEK 293 cells,
交差性
human, mouse
アプリケーション
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
抗PDE4B抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, guinea pig, horse, human, mouse, rat
アプリケーション
western blot
Small Molecule - Inhibitor
Proteins
製品番号
詳細
Species
PDE4B1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Species
rat