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Merck

SVIL

supervillin

別名:
Species:
UniProtKB ID:
遺伝子ID:
  • Human(6840) Summary: This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Two transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Jul 2008]
  • Mouse(225115) supervillin
  • Rat(361256) supervillin
  • cow(281509) supervillin
  • dog(477965) supervillin
  • domestic cat(101098723) supervillin
  • domestic guinea pig(100729448) supervillin
  • Horse(100063045) supervillin
  • naked mole-rat(101713658) supervillin
  • chicken(420475) supervillin
  • sheep(101119493) supervillin

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-SVIL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti-SVIL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
交差性
human
アプリケーション
immunohistochemistry