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PHR2016

Olmesartan Medoxomil Related Compound A

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

3,6-Dihydro-6,6-dimethyl-2-propyl-3-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-4H-furo[3,4-d]imidazol-4-one, 1-{[2′-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl}-4,4-dimethyl-2-propyl-1H-furo[3,4-d]imidazol-6(4H)-one

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About This Item

Empirical Formula (Hill Notation):
C24H24N6O2
CAS Number:
849206-43-5
Molecular Weight:
428.49
UNSPSC Code:
41116107
NACRES:
NA.24

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Product Name

Olmesartan Medoxomil Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

SMILES string

[nH]1nnnc1c2c(cccc2)c3ccc(cc3)C[n]4c5c(nc4CCC)C(OC5=O)(C)C

InChI

1S/C24H24N6O2/c1-4-7-19-25-21-20(23(31)32-24(21,2)3)30(19)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-26-28-29-27-22/h5-6,8-13H,4,7,14H2,1-3H3,(H,26,27,28,29)

InChI key

JUQNVWFXORBZQJ-UHFFFAOYSA-N

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1478378

API family

olmesartan

CofA

current certificate can be downloaded

packaging

pkg of 40 mg

application(s)

pharmaceutical

format

neat

storage temp.

-10 to -25°C

Quality Level

300

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Olmesartan Medoxomil Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material

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PHR2016

Olmesartan Medoxomil Related Compound A

Valsartan Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1875

Valsartan Related Compound A

Irbesartan Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1958

Irbesartan Related Compound A

Candesartan Cilexetil Related Compound B Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR2018

Candesartan Cilexetil Related Compound B

application(s)

pharmaceutical

application(s)

pharmaceutical small molecule

application(s)

pharmaceutical

application(s)

pharmaceutical

format

neat

format

neat

format

-

format

neat

Quality Level

300

Quality Level

300

Quality Level

300

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, pharmaceutical secondary standard

storage temp.

-10 to -25°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

packaging

pkg of 40 mg

packaging

pkg of 30 mg

packaging

pkg of 50 mg

packaging

pkg of 20 mg

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

Olmesartan medoxomil may be used as a secondary pharma standard for the determination of the analyte in pharmaceutical formulations[1][2] using different analytical techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Olmesartan Medoxomil Related Compound A is found as an impurity of olmesartan medoxomil. Olmesartan medoxomil is a specific angiotensin II type 1 antagonist, which is widely used as an antihypertensive agent for the treatment of hypertension.[1]

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB5323 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Validated absorption factor spectrophotometric and reversed-phase high-performance liquid chromatographic methods for the determination of ramipril and olmesartan medoxomil in pharmaceutical formulations
Patel VC, et al.
Eurasian Journal of Analytical Chemistry, 2(3), 159-171 (2007)
Simultaneous determination of olmesartan medoxomil and irbesartan and hydrochlorothiazide in pharmaceutical formulations and human serum using high performance liquid chromatography
Sultana N, et al.
Se Pu / Chinese Journal of Chromatography, 26(5), 544-549 (2008)

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