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70050

Myricetin

≥96.0% (HPLC)

Synonym(s):

3,3′,4′,5,5′,7-Hexahydroxyflavone, Cannabiscetin, Myricetol

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Pack SizeSKUAvailabilityPrice
25 mg
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$246.00
100 mg
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$716.00

About This Item

Empirical Formula (Hill Notation):
C15H10O8
CAS Number:
529-44-2
Molecular Weight:
318.24
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
57652239
EC Number:
208-463-2
Beilstein/REAXYS Number:
332331
MDL number:
MFCD00006827

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Quality Level

200

assay

≥96.0% (HPLC)

form

powder

mp

≥300 °C, >300 °C (lit.)

solubility

ethanol: 10 mg/mL, clear to very faintly turbid, yellow to very deep greenish-yellow

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

SMILES string

Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3cc(O)c(O)c(O)c3

InChI

1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H

InChI key

IKMDFBPHZNJCSN-UHFFFAOYSA-N

Gene Information

human ... CYP1A2(1544)
mouse ... Hexa(15211)
rat ... Il4(287287), Tnf(24835)

General description

Myricetin (MYR) is a natural polyhydroxyflavonol compound, first isolated from the bark of Morella rubra (Myrica rubra) tree.[1]

Application

Myricetin has been used:
  • to study its preventive effect as an antioxidant on noise-induced hearing loss (NIHL) in rats[2]
  • as a flavonoid compound to test antiviral activity of Bourbon virus (BRBV) and in inhibition of RNA-dependent RNA polymerase (RdRP)[3]
  • to study its effect as a treatment on biofilms of Streptococcus mutans and Candida albicans[4]
  • as a reference standard for the quantification of phenolic compounds from Juniperus species[5]

Biochem/physiol Actions

Myricetin exerts anti-oxidant effects[6], and anti-inflammatory effects by regulating multiple signal pathways.[1] It also displays anti-diabetic[1] and hepatoprotective effects.[6] Myricetin strongly inhibits yeast α-glucosidase, glyoxalase I in vitro, and bovine milk xanthine oxidase. It also promotes complex formation between DNA and both topoisomerase I and II, an effect that may have implications in cancer chemotherapy.[7] Myricetin also has various nutraceuticals values and therapeutic effects.[1][6]

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This Item
M676089013476275
Myricetin ≥96.0% (HPLC)

Sigma-Aldrich

70050

Myricetin

Myricetin ≥96.0%, crystalline

Sigma-Aldrich

M6760

Myricetin

Myricetin certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

89013

Myricetin

Myricetin A cell-permeable flavanoid that displays anti-inflammatory, anti-diabetic and anti-cancer properties.

Sigma-Aldrich

476275

Myricetin

form

powder

form

crystalline

form

-

form

solid

assay

≥96.0% (HPLC)

assay

≥96.0%

assay

-

assay

≥98% (HPLC)

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

-

application(s)

food and beverages

application(s)

-

Quality Level

200

Quality Level

100

Quality Level

300

Quality Level

100

solubility

ethanol: 10 mg/mL, clear to very faintly turbid, yellow to very deep greenish-yellow

solubility

absolute ethanol: 10 mg/mL, clear to slightly hazy, yellow to very deep greenish-yellow

solubility

-

solubility

DMSO: 5 mg/mL

mp

≥300 °C, >300 °C (lit.)

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

-

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN2343
BCCM6369
BCCK8931
BCCJ3198
BCCH3611

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Protocols

HPLC Analysis of Flavonoids on Ascentis® RP-Amide

Protocol for HPLC Analysis of Flavonoids on Ascentis® RP-Amide

Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Guilherme Roncari Rocha et al.
BMC complementary and alternative medicine, 18(1), 61-61 (2018-02-16)
Dental caries is considered a multifactorial disease, in which microorganisms play an important role. The diet is decisive in the biofilm formation because it provides the necessary resources for cellular growth and exopolysaccharides synthesis. Exopolysaccharides are the main components of
R.B. Brandt et al.
International Journal of Quantum Chemistry, 11, 195-195 (1984)
Miguel López-Lázaro et al.
Mutation research, 696(1), 41-47 (2009-12-23)
DNA topoisomerases (topos) are the target of several drugs commonly used in cancer chemotherapy; these drugs induce topo-DNA complexes with either topo I or topo II that eventually trigger cell death. The inhibition of these enzymes induces DNA alterations that
View All Related Papers

Global Trade Item Number

SKUGTIN
SMB01348-100MG04065267542324
SMB01348-25MG04065267542331
70050-25MG04061832795720
70050-100MG04061832795706

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