Cephalexin hydrate (C4895) is soluble in DMSO and methanol.
C4895
Cephalexin hydrate
first-generation cephalosporin antibiotic
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| Size/SKU | Availability | Price |
|---|---|---|
5 g | Available to ship TODAYfromMILWAUKEE | $147.00 |
10 g | Available to ship TODAYfromMILWAUKEE | $262.00 |
25 g | Available to ship TODAYfromMILWAUKEE | $504.00 |
About This Item
Empirical Formula (Hill Notation):
C16H17N3O4S · xH2O
CAS Number:
Molecular Weight:
347.39 (anhydrous basis)
PubChem Substance ID:
UNSPSC Code:
51282503
NACRES:
NA.85
EC Number:
239-773-6
MDL number:
Beilstein/REAXYS Number:
965503
Quality Segment
form
powder
pKa
7.3, 5.2
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
cell wall synthesis | interferes
storage temp.
2-8°C
SMILES string
S1C2N(C(=C(C1)C)C(=O)O)C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3.O
InChI
1S/C16H17N3O4S.H2O/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9;/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23);1H2/t10-,11-,15?;/m1./s1
InChI key
AVGYWQBCYZHHPN-FNOHQHCYSA-N
General description
Chemical structure: β-lactam
Application
Cephalexin is a cephalosporin antibiotic used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.
Biochem/physiol Actions
Cephalexin disrupts the synthesis of the peptidoglycan layer of bacterial cell walls which is responsible for cell wall structural integrity. Peptidoglycan synthesis is facilitated by transpeptidases known as penicillin-binding proteins (PBPs). PBPs bind to the D-Ala-D-Ala at the end of muropeptides (peptidoglycan precursors) to crosslink the peptidoglycan. Cephalexin antibiotics mimic the D-Ala-D-Ala site, thereby competitively inhibiting PBP crosslinking of peptidoglycan.
Other Notes
Storage of this product should be in airtight containers and protected from light.
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This Item | ||
|---|---|---|
| description first-generation cephalosporin antibiotic | description United States Pharmacopeia (USP) Reference Standard | description United States Pharmacopeia (USP) Reference Standard |
| antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum - | antibiotic activity spectrum - |
| Quality Level 200 | Quality Level - | Quality Level - |
| form powder | form - | form - |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. 2-8°C |
| pKa 5.2 | pKa - | pKa - |
| mode of action cell wall synthesis | interferes | mode of action - | mode of action - |
Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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What solvent should I use to dissolve item C4895, Cephalexin hydrate?
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how many are in the bottles
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This product is supplied in powder form and is currently available in 5 gram, 10 gram, and 25 gram pack sizes. This product is intended for research use only and is unsuitable for human or veterinary use.
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