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J2000

Juvenile hormone III

≥65%, liquid, non-sterile

Synonym(s):

Methyl farnesoate, 10,11-epoxide, C16-Juvenile Hormone, JH-III, Manduca hormone, trans,trans-10,11-Epoxy-3,7,11-trimethyl-2,6-dodecadienic acid methyl ester

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Pack SizeSKUAvailabilityPrice
10 mg
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$321.00
50 mg
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$1,270.00
$1,079.50

About This Item

Empirical Formula (Hill Notation):
C16H26O3
CAS Number:
24198-95-6
Molecular Weight:
266.38
UNSPSC Code:
51111800
NACRES:
NA.32
PubChem Substance ID:
24896191
EC Number:
246-072-9
Beilstein/REAXYS Number:
1316317
MDL number:
MFCD00135990
Biological source:
synthetic (organic)
Form:
liquid
Assay:
≥65% (HPLC)

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biological source

synthetic (organic)

Quality Level

200

sterility

non-sterile

assay

≥65% (HPLC)

form

liquid

concentration

≥65%

technique(s)

activity assay: suitable

shipped in

ambient

storage temp.

−20°C

SMILES string

COC(=O)\C=C(/C)CC\C=C(/C)CC[C@H]1OC1(C)C

InChI

1S/C16H26O3/c1-12(9-10-14-16(3,4)19-14)7-6-8-13(2)11-15(17)18-5/h7,11,14H,6,8-10H2,1-5H3/b12-7+,13-11+

InChI key

QVJMXSGZTCGLHZ-ZPLWXOMKSA-N

General description

Research Area: Cell Signaling

Juvenile hormone III (JH III) is the most prevalent juvenile hormone (JH) found in insects.[1]

Application

Juvenile hormone III has been used to:
  • study the effect of juvenile hormone on mictic (sexual) female production of the rotifer Brachionus plicatilis Muller[2]
  • study the effect of juvenile hormone on head GB19811 (putative Takeout/juvenile hormone binding protein) mRNA levels in adult honeybees[3]
  • study the effect of juvenile hormone on gonadotropic and physiological functions in bumblebee Bombus terrestris[4]

Biochem/physiol Actions

Controls the larval metamorphosis of insects, including the retention of juvenile characteristics.
JHBPs (JH-binding proteins) protect JH (juvenile hormone) from JH esterase- and epoxide hydrolase-mediated degradation. They also help in delivering JH to target tissues.[5]Juvenile hormones(JHs) are a group of acyclic sesquiterpenoids, and in some insect lineages, the farnesol backbone of these compounds undergoes chemical modification to produce a homologous series of hormones. JH is essential for insect development and reproduction in every aspect. It plays a key role in metamorphosis and caste determination in social insects. It modulates behavior, polyphenism, larval and adult diapause, and ovarian development.[1] The sesquiterpenoid backbone of juvenile hormone III (JH III) is biosynthesized through the classical mevalonate (MVA) pathway in cockroaches.[6]

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This Item
M6682A0423T9265
Juvenile hormone III ≥65%, liquid, non-sterile

Sigma-Aldrich

J2000

Juvenile hormone III

Methoprene acid ≥98% (TLC)

Sigma-Aldrich

M6682

Methoprene acid

Adrenocorticotropic Hormone human ≥97% (HPLC)

Sigma-Aldrich

A0423

Adrenocorticotropic Hormone human

Thyrotropic hormone from human pituitary lyophilized powder, ≥6.2 IU/mg (immunoassay, non-sterile)

Sigma-Aldrich

T9265

Thyrotropic hormone from human pituitary

biological source

synthetic (organic)

biological source

-

biological source

synthetic (organic)

biological source

human pituitary glands

assay

≥65% (HPLC)

assay

≥98% (TLC)

assay

≥97% (HPLC)

assay

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

technique(s)

activity assay: suitable

technique(s)

-

technique(s)

-

technique(s)

cell culture | mammalian: suitable

concentration

≥65%

concentration

-

concentration

-

concentration

-

form

liquid

form

-

form

powder

form

lyophilized powder

hcodes

H413

Hazard Classifications

Aquatic Chronic 4

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000478681
0000478681
0000426650
0000426650
0000277821

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Linquan Ge et al.
Frontiers in physiology, 11, 579233-579233 (2020-10-13)
The mirid bug, Cyrtorhinus lividipennis Reuter, is an important predator of rice planthoppers in Asia. In a previous study, C. lividipennis fed on gramineous weeds with brown planthopper (BPH) eggs had reduced development compared to those fed on rice with
A Ishikawa et al.
Insect molecular biology, 21(1), 49-60 (2011-10-13)
Most aphids show reproductive polyphenism, i.e. they alternate their reproductive modes from parthenogenesis to sexual reproduction in response to short photoperiods. Although juvenile hormone (JH) has been considered a likely candidate for regulating the transition from asexual to sexual reproduction
Tzachi Hagai et al.
Insect biochemistry and molecular biology, 37(7), 689-701 (2007-06-07)
We identified and characterized eight genes encoding putative Takeout/juvenile hormone binding proteins (To/JHBP) in the honeybee genome. Phylogenetic analyses revealed nine distinct lineages within this gene family, including those containing Takeout (To) and JHBP for which there are no honeybee
View All Related Papers

Global Trade Item Number

SKUGTIN
J2000-50MG04061833271865
J2000-10MG04061833866221

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