SYNPLE-R001

Reagent-cartridge Reductive Amination

Synple

• Synonym(s): Synple 2
• UNSPSC Code: 12161503
• NACRES: NA.22
• MDL number: MFCD32903606

Properties

• Quality Level: 100
• reaction suitability: reaction type: Reductive Aminations
• parameter: up to 0.5 mmol scale
• SMILES string: [s]1cnc(c1c2ccc(cc2)CNC(=O)[C@H]3N(C[C@@H](C3)O)C(=O)[C@@H](NC(=O)CCOCCC(=O)O)C(C)(C)C)C
• InChI key: HVPZHRHEHKZOOJ-TYBLODHISA-N

Description

General description

Reagent-cartridge Reductive Amination is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the reductive amination of aldehydes and ketones. The cartridge contains all necessary reagents for condensation, reduction, and purification.

Scale: up to 0.5 mmol
Compatible substrates: aldehydes, ketones, primary amines, secondary amines

Cartridge contents:

• Reducing agent (supported cyanoborohydride)
• Proton source (Phenylacetic acid)
• SCX (for purification)
• Supported benzaldehyde (amine scavenger)

Learn more about the Synple automated synthesis platform.

Features and Benefits of Synple Platform

• Time savings - pre-installed protocols have been highly optimized, which obviates the need for the user′s own reaction development and optimization
• Easy to use - protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
• Safety - all chemicals are contained in the system, minimizing the user′s exposure
• Set-up reaction in less than 5 minutes
• Small footprint
• Plug & Play system - simple installation
• Reaction temperatures from 25 °C - 80 °C
• Cartridges available for many different reactions
• Prefilled with all required reagents
• RFID chip containing optimized reaction protocol

Other Notes

An integrated console for capsule-based, automated organic synthesis

Legal Information

Product of Synple Chem AG

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable