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D0195

Dimethylethylammoniumpropane sulfonate

≥97% (TLC)

Synonym(s):

NDSB 195

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5 g

Available to ship TODAYfromMILWAUKEE

$201.00

About This Item

Empirical Formula (Hill Notation):
C7H17NO3S
CAS Number:
160255-06-1
Molecular Weight:
195.28
MDL number:
MFCD01319124
UNSPSC Code:
12161900
NACRES:
NA.25

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description

zwitterionic

Quality Level

100

assay

≥97% (TLC)

form

powder

mol wt

195.28 g/mol

technique(s)

LC/MS: suitable, protein quantification: suitable

color

white

application(s)

detection

storage temp.

room temp

SMILES string

[S](=O)(=O)([O-])CCC[N+](CC)(C)C

InChI key

NNCRHRDBFDCWPA-UHFFFAOYSA-N

General description

Dimethylethylammoniumpropane sulfonate is a zwitterionic solubilizing agent with usefulness in protein crystallization. [1]

Application

Dimethylethylammoniumpropane sulfonate has been used in a study to assess the functional properties of the separate subunits of the human DNA helicase II/Ku autoantigen. [2] It has also been used in a study to investigate the swelling behaviors of copolymeric hydrogels in various saline solutions.
Non-detergent sulfobetaine is a compound used for non-denaturing protien purification. Increases the extraction yield of membrane, nuclear and cytoskeletal associated proteins. Zwitterionic over a wide pH range, easily removed by dialysis and no significant absorption in the near UV range. Specific applications include microsomal protein extraction, nuclear protein recovery, precipitation reduction in IEF, and membrane-bound protease purification.

Other Notes

This product is non-micelle forming.

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This Item
48000140772D4266
Dimethylethylammoniumpropane sulfonate ≥97% (TLC)

Sigma-Aldrich

D0195

Dimethylethylammoniumpropane sulfonate

NDSB-195 A non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins.

Millipore

480001

NDSB-195

3-(N,N-Dimethylmyristylammonio)propanesulfonate ≥98.0% (TLC)

Sigma-Aldrich

40772

3-(N,N-Dimethylmyristylammonio)propanesulfonate

3-(Decyldimethylammonio)­propane­sulfonate inner salt zwitterionic detergent

Sigma-Aldrich

D4266

3-(Decyldimethylammonio)­propane­sulfonate inner salt

form

powder

form

solid

form

powder

form

powder

assay

≥97% (TLC)

assay

≥95% (TLC)

assay

≥98.0% (TLC)

assay

≥98.0% (TLC)

technique(s)

LC/MS: suitable, protein quantification: suitable

technique(s)

-

technique(s)

nucleic acid detection: suitable, protein purification: suitable, protein quantification: suitable

technique(s)

enzyme immunoassay: suitable, protein purification: suitable, protein quantification: suitable

application(s)

detection

application(s)

-

application(s)

-

application(s)

-

storage temp.

room temp

storage temp.

15-25°C

storage temp.

-

storage temp.

-

mol wt

195.28 g/mol

mol wt

-

mol wt

micellar avg mol wt 30,200

mol wt

micellar avg mol wt 12,600

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
MKDB2890
MKDB7584
MKCZ2073
MKCX1010
MKCQ9616

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Thermoreversible hydrogels XIII: Synthesis and swelling behaviors of [N-isopropylacrylamide-co-sodium 2-acrylamido-2-methylpropyl sulfonate-co-N,N-dimethyl(acrylamido propyl) ammonium propane sulfonate] copolymeric hydrogels
Lee, W. and W. Yuan
Journal of Polymer Research, 7, 29-29 (2000)
A E Ochem et al.
The Journal of biological chemistry, 272(47), 29919-29926 (1997-12-31)
The Ku antigen consists of two subunits of 70 and 83 kDa and is endowed with both duplex DNA end-binding capacity and helicase activity (human DNA helicase II). HeLa Ku can be isolated from in vitro cultured human cells uniquely
L Vuillard et al.
FEBS letters, 353(3), 294-296 (1994-10-24)
The potential usefulness of the new zwitterionic solubilizing agent, dimethyl ethylammonium propane sulfonate (NDSB195), in protein crystallization was shown using hen egg-white lysozyme. In the presence of this agent, highly diffracting crystals were obtained using ammonium sulphate as a precipitant

Global Trade Item Number

SKUGTIN
D0195-5G04061833610404

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